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David H Sachs Selected Research

Heterologous Transplantation (Xenotransplantation)

11/2021Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig-to-baboon xenotransplantation.
1/2018Absence of interaction between porcine endogenous retrovirus and porcine cytomegalovirus in pig-to-baboon renal xenotransplantation in vivo.
9/2014Increased transfusion-free survival following auxiliary pig liver xenotransplantation.
8/2014Porcine cytomegalovirus infection is associated with early rejection of kidney grafts in a pig to baboon xenotransplantation model.
7/2012Up to 9-day survival and control of thrombocytopenia following alpha1,3-galactosyl transferase knockout swine liver xenotransplantation in baboons.
1/2005Early weaning of piglets fails to exclude porcine lymphotropic herpesvirus.
12/2004T cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation model.
5/2004Activation of porcine cytomegalovirus, but not porcine lymphotropic herpesvirus, in pig-to-baboon xenotransplantation.
9/2003Reduced efficacy of ganciclovir against porcine and baboon cytomegalovirus in pig-to-baboon xenotransplantation.
6/2003Porcine cytomegalovirus and coagulopathy in pig-to-primate xenotransplantation.
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David H Sachs Research Topics

Disease

18Neoplasms (Cancer)
11/2019 - 05/2002
10Graft vs Host Disease (Graft-Versus-Host Disease)
11/2016 - 08/2002
7Autoimmune Diseases (Autoimmune Disease)
04/2016 - 06/2003
5Chronic Kidney Failure (Chronic Renal Failure)
11/2019 - 11/2002
5Lymphoproliferative Disorders (Lymphoproliferative Disorder)
10/2015 - 05/2004
4B-Cell Lymphoma (Lymphoma, B Cell)
01/2019 - 04/2012
4Inflammation (Inflammations)
08/2018 - 05/2017
4Wounds and Injuries (Trauma)
01/2018 - 05/2015
4Infections
08/2012 - 05/2002
3Multiple Myeloma
11/2019 - 11/2002
3Burns
11/2017 - 06/2014
3Hyperglycemia
11/2017 - 11/2002
3Thrombocytopenia (Thrombopenia)
09/2014 - 07/2012
3Hematologic Neoplasms (Hematological Malignancy)
07/2007 - 05/2003
3Thrombosis (Thrombus)
05/2007 - 11/2003
2Proteinuria
11/2021 - 10/2018
2Fibrosis (Cirrhosis)
08/2018 - 05/2002
2Pain (Aches)
01/2018 - 08/2012
2Hemorrhage
09/2014 - 02/2012
2Body Weight (Weight, Body)
10/2010 - 01/2007
2Leukemia
06/2010 - 09/2002
1Nephrotic Syndrome (Syndrome, Nephrotic)
11/2021
1Neoplasm Metastasis (Metastasis)
08/2018
1Coinfection
01/2018
1Brain Diseases (Brain Disorder)
01/2018
1Ascites
01/2018
1Liver Failure
01/2018
1Diabetic Nephropathies (Diabetic Nephropathy)
11/2017
1Cicatrix (Scar)
05/2017
1Residual Neoplasm
01/2017
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
01/2017
1Acute Liver Failure (Fulminant Hepatic Failure)
01/2017
1Reperfusion Injury
01/2016
1Myocardial Infarction
01/2016
1Infarction (Infarctions)
01/2016
1Left Ventricular Dysfunction
01/2016
1Myocardial Ischemia (Ischemic Heart Diseases)
01/2016
1Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia)
08/2015
1Cytomegalovirus Infections (Inclusion Disease)
08/2014
1Ischemia
08/2013

Drug/Important Bio-Agent (IBA)

7Cyclosporine (Ciclosporin)FDA LinkGeneric
01/2018 - 08/2002
7Immunotoxins (Immunotoxin)IBA
01/2018 - 10/2011
5HLA Antigens (Human Leukocyte Antigens)IBA
11/2017 - 11/2002
5Monoclonal AntibodiesIBA
01/2016 - 05/2003
4Diphtheria ToxinIBA
01/2018 - 08/2012
4Interleukin-2 Receptors (IL 2 Receptor)IBA
01/2017 - 05/2013
4Proteins (Proteins, Gene)FDA Link
08/2015 - 06/2003
4CytokinesIBA
12/2012 - 09/2003
3AntigensIBA
11/2019 - 09/2002
3Indicators and Reagents (Reagents)IBA
03/2014 - 10/2011
2Freund's AdjuvantIBA
08/2018 - 01/2018
2Galectin 3 (LGALS3)IBA
08/2018 - 10/2017
2Immunoglobulin M (IgM)IBA
05/2017 - 01/2016
2Pharmaceutical PreparationsIBA
01/2017 - 08/2015
2TransferasesIBA
07/2012 - 05/2007
2DNA (Deoxyribonucleic Acid)IBA
09/2003 - 05/2002
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
05/2003 - 11/2002
1LigandsIBA
11/2021
1swine leukocyte antigenIBA
01/2019
1Abatacept (Orencia)FDA Link
10/2018
1LectinsIBA
08/2018
1Biological ProductsIBA
08/2018
1Immunosuppressive Agents (Immunosuppressants)IBA
01/2018
1BilirubinIBA
01/2018
1Tacrolimus (Prograf)FDA LinkGeneric
01/2018
1Glucose (Dextrose)FDA LinkGeneric
11/2017
1brassIBA
05/2017
1AutoantibodiesIBA
05/2017
1Myosins (Myosin)IBA
05/2017
1Peptides (Polypeptides)IBA
05/2017
1Interleukin-2 (IL2)IBA
01/2017
1Troponin T (Troponin T1)IBA
01/2016
1Myosin Heavy Chains (Myosin Heavy Chain)IBA
01/2016
1TroponinIBA
01/2016
1Protein Isoforms (Isoforms)IBA
08/2015
1CCR4 ReceptorsIBA
08/2015
1CarbohydratesIBA
05/2015
1AnticoagulantsIBA
09/2014
1Immunologic Factors (Immunomodulators)IBA
08/2013

Therapy/Procedure

12Therapeutics
01/2019 - 08/2004
12Transplantation
01/2019 - 11/2002
11Heterologous Transplantation (Xenotransplantation)
11/2021 - 05/2002
9Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2013 - 08/2002
8Cell Transplantation
10/2015 - 08/2004
5Kidney Transplantation
11/2019 - 05/2002
2Islets of Langerhans Transplantation
11/2017 - 11/2002
2Organ Transplantation
08/2012 - 04/2012
2Stem Cell Transplantation
01/2005 - 05/2003
1Intravenous Injections
01/2019
1Blood Component Removal (Apheresis)
08/2018
1Hepatectomy
01/2018
1Liver Transplantation
01/2018
1Glycemic Control
11/2017
1Facial Transplantation
11/2017
1Vascularized Composite Allotransplantation
11/2017
1Euthanasia (Mercy Killing)
01/2017
1Cell- and Tissue-Based Therapy (Cell Therapy)
01/2017
1Homologous Transplantation
01/2017
1Skin Transplantation (Skin Grafting)
06/2014
1Artificial Skin
06/2014